Article
Polymorphisms in the promoter region of relaxin-2 and preterm birth: involvement of relaxin in the etiology of preterm birth.
In vivo (Athens, Greece) - 1 Jan 2000
Vogel Ida, Hollegaard Mads Vilhelm, Hougaard David Michael, Thorsen Poul, Grove Jakob
Abstract excerpt
BACKGROUND: Circulating relaxin levels have repeatedly been associated with preterm birth (PTB). Our aim was to investigate if mothers carrying promoter single nucleotide polymorphisms (SNPs) in one of the three relaxin genes (RLN1, RLN2, RLN3) are predisposed for PTB. PATIENTS AND METHODS: Maternal DNA from 80 preterm cases (40 very preterm births (24-34 weeks) and 40 moderate preterm (34-36 weeks) and 40...
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