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Article

Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling.

Cardiovascular research - 1 Sept 2013

Whittington Hannah J, Harding Idris, Stephenson Clemency I M, Bell Robert, Hausenloy Derek J, Mocanu Mihaela M, Yellon Derek M

Abstract excerpt

AIMS: Old age and diabetes are risk factors that often coexist increasing the vulnerability of the heart to the lethal effects of ischaemia-reperfusion injury (IRI). However, to our knowledge, no investigations have examined IRI and cardioprotective signalling in animal models bearing these co-morbidities concomitantly. The ability of the heart to recover following IRI is greatly dependent on its innate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23723063
DOI: 10.1093/cvr/cvt140
PMCID: PMC3746954

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PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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