Article
Diversity of cwp loci in clinical isolates of Clostridium difficile.
Journal of medical microbiology - 1 Sept 2013
Biazzo Manuele, Cioncada Rossella, Fiaschi Luigi, Tedde Vittorio, Spigaglia Patrizia, Mastrantonio Paola, Pizza Mariagrazia, Barocchi Michèle A, Scarselli Maria, Galeotti Cesira L
Abstract excerpt
An increased incidence of Clostridium difficile infection (CDI) is associated with the emergence of epidemic strains characterized by high genetic diversity. Among the factors that may have a role in CDI is a family of 29 paralogues, the cell-wall proteins (CWPs), which compose the outer layer of the bacterial cell and are likely to be involved in colonization. Previous studies have shown that 12 of the 29 cwp...
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