Article
Functional association of interleukin 18 gene -607 (C/A) promoter polymorphisms with disease course in Chinese patients with adult-onset Still's disease.
The Journal of rheumatology - 1 Oct 2009
Chen Der-Yuan, Chen Yi-Ming, Chen Hsin-Hua, Hsieh Chia-Wei, Lin Chi-Chen, Lan Joung-Liang
Abstract excerpt
OBJECTIVE: Interleukin 18 (IL-18) has a central role in the pathogenesis of adult-onset Still's disease (AOSD). We investigated the functional association of -607 (C/A) IL-18 promoter polymorphisms with disease course in Chinese patients with AOSD. METHODS: Sequence-specific primer polymerase cha...
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