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Article

Association study of genetic variants in miRNAs in patients with inflammatory bowel disease: preliminary results.

Digestive diseases and sciences - 1 Aug 2013

Gazouli Maria, Papaconstantinou Ioannis, Stamatis Konstantinos, Vaiopoulou Anna, Zeglinas Christos, Vassiliou Ioannis, Giokas Georgios, Tzathas Charalampos

Abstract excerpt

BACKGROUND: Aberrant expression and structural alteration of miRNAs are considered to participate in inflammation and cancer development. It has been suggested that common single-nucleotide polymorphisms (SNPs) in miRNAs are associated with susceptibility to several human diseases. METHODS: In the present preliminary study we evaluated the associations of two SNPs (rs2910164 and rs11614913 in miR-146a and...

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PMID: 23543085
DOI: 10.1007/s10620-013-2640-y

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