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Article

Temporal changes in resistance mechanisms in colonizing Escherichia coli isolates with reduced susceptibility to fluoroquinolones.

Diagnostic microbiology and infectious disease - 1 Aug 2013

Han Jennifer H, Nachamkin Irving, Tolomeo Pam, Mao Xiangqun, Bilker Warren B, Lautenbach Ebbing

Abstract excerpt

The objective of this study was to characterize the temporal variability of fluoroquinolone resistance mechanisms among Escherichia coli colonizing the gastrointestinal tract of hospitalized patients. Patients with new fluoroquinolone-resistant E. coli (FQREC) colonization were followed with serial fecal sampling until discharge or death. Genetic mechanism(s) of resistance for all FQREC isolates was...

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Identifiers

PMID: 23719087
DOI: 10.1016/j.diagmicrobio.2013.04.018
PMCID: PMC3725193

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