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Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.

Antimicrobial agents and chemotherapy - 1 Oct 2003

Komp Lindgren Patricia, Karlsson Asa, Hughes Diarmaid

Abstract excerpt

Escherichia coli strains from patients with uncomplicated urinary tract infections were examined by DNA sequencing for fluoroquinolone resistance-associated mutations in six genes: gyrA, gyrB, parC, parE, marOR, and acrR. The 54 strains analyzed had a susceptibility range distributed across 15 dilutions of the fluoroquinolone MICs. There was a correlation between the fluoroquinolone MIC and the number of...

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Source

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Identifiers

PMID: 14506034
DOI: 10.1128/AAC.47.10.3222-3232.2003
PMCID: PMC201150

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Source receipt: pubmed, retrieved 7 Sept 2026.

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