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Article

The env gene variability is not directly related to the high cytopathogenicity of an HIV1 variant.

Virology - 1 Aug 1990

Spire B, Hirsch I, Neuveut C, Sire J, Chermann J C

Abstract excerpt

HIV1-NDK is a Zairian HIV1 isolate which is unique because of its high cytopathic effect on T lymphoblastoid cell lines. Its sequence analysis has indicated 30% divergence with HIV1-LAV/BRU HTLVIII B prototype in the env gene encoding for the envelope glycoprotein gp120. In order to correlate the highly cytopathic properties with the env genetic variability, recombinants between the HIV1 prototype and HIV1-NDK...

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PMID: 2371777
DOI: 10.1016/0042-6822(90)90543-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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