Article
Structural variability of env and gag gene products from a highly cytopathic strain of HIV-1.
Archives of virology - 1 Jan 1992
Yahi N, Fantini J, Hirsch I, Chermann J C
Abstract excerpt
The glycoprotein precursor of the highly cytopathic Zairian virus HIV1-NDK synthesized in CEM leukemic cells displayed a molecular mass of 140 kDa (gp140) as compared to the 160 kDa of gp160 of HIV1-LAV prototype strain. This precursor was cleaved to produce a smaller than prototype extra-cellula...
Topics
- Amidohydrolases
- Cytopathogenic Effect, Viral
- Gene Products, env
- Gene Products, gag
- Genetic Variation
- Glycosylation
- HIV-1
- Humans
- Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
- Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
- Tumor Cells, Cultured
