Article
Structural variability of env and gag gene products from a highly cytopathic strain of HIV-1.
Archives of virology - 1 Jan 1992
Yahi N, Fantini J, Hirsch I, Chermann J C
Abstract excerpt
The glycoprotein precursor of the highly cytopathic Zairian virus HIV1-NDK synthesized in CEM leukemic cells displayed a molecular mass of 140 kDa (gp140) as compared to the 160 kDa of gp160 of HIV1-LAV prototype strain. This precursor was cleaved to produce a smaller than prototype extra-cellular envelope glycoprotein (gp100) and a transmembrane component with a usual size (gp41). Immunoprecipitates from...
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