Article

Targeted Nanoencapsulation of Tunicamycin Reduces Toxicity While Improving its Therapeutic Effectiveness in Pancreatic Cancer Cells

2025-05-23

Abstract excerpt

<title>Abstract</title> <p>Pancreatic ductal adenocarcinoma (PDAC) remains one of the leading sources of cancer mortality worldwide. An initial response to chemotherapy, such as Gemcitabine (GEM) alone or in combination with other chemotherapies, is often followed by emergent resistance, underscoring the urgent need for targeted therapies. PDAC cells are highly addicted to oncogenic K-RAS mutations for their grow...

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Literature Corpus work: a6c69974-032d-5cd6-8da3-9ffbff2643f6
DOI: 10.21203/rs.3.rs-6711378/v1

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