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Caloric restriction augments radiation efficacy in breast cancer

15 Jun 2013

Abstract excerpt

Dietary modification such as caloric restriction (CR) has been shown to decrease tumor initiation and progression. We sought to determine if nutrient restriction could be used as a novel therapeutic intervention to enhance cytotoxic therapies such as radiation (IR) and alter the molecular profile of triple-negative breast cancer (TNBC), which displays a poor prognosis. In two murine models of TNBC, significant...

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PMID: 23708519
DOI: 10.4161/cc.25016

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