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Article

Disadvantage of Social Sensitivity: Interaction of Oxytocin Receptor Genotype and Child Maltreatment on Brain Structure.

Biological psychiatry - 1 Sept 2016

Dannlowski Udo, Kugel Harald, Grotegerd Dominik, Redlich Ronny, Opel Nils, Dohm Katharina, Zaremba Dario, Grögler Anne, Schwieren Juliane, Suslow Thomas, Ohrmann Patricia, Bauer Jochen, Krug Axel, Kircher Tilo, Jansen Andreas, Domschke Katharina, Hohoff Christa, Zwitserlood Pienie, Heinrichs Markus, Arolt Volker, Heindel Walter, Baune Bernhard T

Abstract excerpt

BACKGROUND: Oxytocin has received much attention as a prosocial and anxiolytic neuropeptide. In human studies, the G-allele of a common variant (rs53576) in the oxytocin receptor gene (OXTR) has been associated with protective properties such as reduced stress response and higher receptiveness for social support. In contrast, recent studies suggest a detrimental role of the rs53576 G-allele in the context of...

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Source

Identifiers

PMID: 26858213
DOI: 10.1016/j.biopsych.2015.12.010

Genes

OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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