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Article

[Major gene mutations associated with obesity and diabetes mellitus].

Molekuliarnaia biologiia - 1 Jan 2000

Pankov Iu A

Abstract excerpt

Obesity and diabetes mellitus are associated with low or elevated serum leptin and insulin levels (U-like relation). Mutations in LEP and INS are linked to leptin and insulin decrease while mutations in LEPR and INSR to their increase. Homozygous LEP mutations are associated with the early onset...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23705494
DOI: 10.7868/s0026898413010138

Genes

INS
INSR
LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23705494-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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