Article
[Insulin resistance and metabolic syndrome].
Zeitschrift fur Kardiologie - 1 May 2000
Joost H G, Giesen K, Kluge R, Ortlepp J, Plum L
Abstract excerpt
The metabolic syndrome represents a complex combination of the symptoms obesity, insulin resistance, dyslipoproteinemia, hypertension, and type 2 diabetes. These components have a heterogeneous genetic basis and appear to be closely linked. Obesity is determined by a polygenic constellation and produces insulin resistance, hypertension and dyslipidemia. In addition, defects in the signal transduction of insulin...
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