Article
High levels of hepatitis B virus after the onset of disease lead to chronic infection in patients with acute hepatitis B.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Oct 2013
Yotsuyanagi Hiroshi, Ito Kiyoaki, Yamada Norie, Takahashi Hideaki, Okuse Chiaki, Yasuda Kiyomi, Suzuki Michihiro, Moriya Kyoji, Mizokami Masashi, Miyakawa Yuzo, Koike Kazuhiko
Abstract excerpt
BACKGROUND: Some patients with acute hepatitis B virus (HBV) infection develop chronic infection. However, the method for identifying these patients has not been established. METHODS: We followed 215 Japanese patients with acute HBV infection until the clearance of hepatitis B surface antigen (HBsAg) or the development of chronic infection. Levels of HBsAg and HBV DNA were serially monitored from the onset....
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