Article
A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.
Obesity (Silver Spring, Md.) - 1 Sept 2013
Li Wei-Dong, Jiao Hongxiao, Wang Kai, Zhang Clarence K, Glessner Joseph T, Grant Struan F A, Zhao Hongyu, Hakonarson Hakon, Arlen Price R
Abstract excerpt
OBJECTIVE: To identify plasma uric acid-related genes in extremely obese and normal weight individuals using genome-wide association studies (GWASs). DESIGN AND METHODS: Using genotypes from a GWAS focusing on obesity and thinness, quantitative trait association analyses (PLINK) for plasma uric acid levels in 1,060 extremely obese individuals (BMI > 35 kg/m2) and normal-weight controls (BMI < 25 kg/m2) were...
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