Article
Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.
Pathology international - 1 Jun 2017
Kim Yunjung, Shiba-Ishii Aya, Nakagawa Tomoki, Husni Ryan Edbert, Sakashita Shingo, Takeuchi Tomoyo, Noguchi Masayuki
Abstract excerpt
Alterations of epidermal growth factor receptor (EGFR) expression frequently occur in early-stage lung adenocarcinoma. Ubiquitin-specific protease 8 (USP8) has been reported to stabilize EGFR protein at the plasma membrane through the recycling pathway. Here, we examined the correlation between USP8 expression and the expression or mutation status of EGFR, as well as the clinicopathological features of lung...
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