Article
HapBoost: a fast approach to boosting haplotype association analyses in genome-wide association studies.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Wan Xiang, Yang Can, Yang Qiang, Zhao Hongyu, Yu Weichuan
Abstract excerpt
Genome-wide association study (GWAS) has been successful in identifying genetic variants that are associated with complex human diseases. In GWAS, multilocus association analyses through linkage disequilibrium (LD), named haplotype-based analyses, may have greater power than single-locus analyses for detecting disease susceptibility loci. However, the large number of SNPs genotyped in GWAS poses great...
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