Article
hapConstructor: automatic construction and testing of haplotypes in a Monte Carlo framework.
Bioinformatics (Oxford, England) - 15 Sept 2008
Abo Ryan, Knight Stacey, Wong Jathine, Cox Angela, Camp Nicola J
Abstract excerpt
SUMMARY: Haplotypes carry important information that can direct investigators towards underlying susceptibility variants, and hence multiple tagging single nucleotide polymorphisms (tSNPs) are usually studied in candidate gene association studies. However, it is often unknown which SNPs should be included in haplotype analyses, or which tests should be performed for maximum power. We have developed a program,...
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