Article
Angiotensin-converting-enzyme gene polymorphisms, smoking and chronic obstructive pulmonary disease.
International journal of chronic obstructive pulmonary disease - 1 Jan 2007
Busquets Xavier, MacFarlane Niall G, Heine-Suñer Damià, Morlá Montse, Torres-Juan Laura, Iglesias Amanda, Lladó Jeronia, Sauleda Jaume, Agustí Alvar G N
Abstract excerpt
While tobacco smoking is the main risk factor for chronic obstructive pulmonary disease (COPD) only a fraction of smokers go on to develop the disease. We investigated the relationship between the insertion (I)--deletion (D) polymorphisms in the Angiotensin converting enzyme (ACE) gene and the risk of developing COPD in smokers by determining the distribution of the ACE genotypes (DD, ID and II) in 151 life-long...
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