Article
ACE I allele and eNOS G allele crosstalk may have a role in chronic obstructive pulmonary disease.
Clinical biochemistry - 1 Nov 2004
Ahsan Aarif, Ram Rekhbala, Baig Masroor A, Pasha M A Qadar
Abstract excerpt
BACKGROUND: Pulmonary hypertension, a characteristic of chronic obstructive pulmonary disease (COPD) has led us to investigate polymorphisms in angiotensin-converting enzyme (ACE) and endothelial nitric oxide synthase (eNOS) genes. DESIGN AND METHODS: Sixty-six normal and 27 patients, all of whom were smokers, were screened for ACE Insertion/Deletion (I/D) and eNOS G894T and CA-repeat polymorphisms and for plasma...
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