Effect of the AIR-1 locus on the activation of an enhancerless HLA-DQA1 promoter.

doi:10.1007/BF02115012

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Article

Effect of the AIR-1 locus on the activation of an enhancerless HLA-DQA1 promoter.

Immunogenetics - 1 Jan 1990

Ombra M N, Del Pozzo G, Perfetto C, Maffei A, Guardiola J

Abstract excerpt

Studies on the regulation of a major histocompatibility complex (MHC) class II gene, HLA-DQA1, in Ia-positive cells (Raji, a human B-lymphoma cell line) and in isogenic Ia-negative cells (RJ2.2.5, a mutant of Raji altered at the AIR-1 locus) are reported. As previously found, AIR-1 is required in...

Topics

Base Sequence
Cell Line
Chloramphenicol O-Acetyltransferase
Chromosome Mapping
Gene Expression Regulation
HLA-DQ Antigens
Humans
Molecular Sequence Data
Mutation
Plasmids
Promoter Regions, Genetic
Recombinant Fusion Proteins
Regulatory Sequences, Nucleic Acid
Transfection

Source

Open in PubMed

Identifiers

PMID: 2370082
DOI: 10.1007/BF02115012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2370082-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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