Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Changes in DNA methylation patterns and repetitive sequences in blood lymphocytes of aged horses.

Age (Dordrecht, Netherlands) - 1 Feb 2014

Wnuk Maciej, Lewinska Anna, Gurgul Artur, Zabek Tomasz, Potocki Leszek, Oklejewicz Bernadetta, Bugno-Poniewierska Monika, Wegrzyn Magdalena, Slota Ewa

Abstract excerpt

It is known that aged organisms have modified epigenomes. Epigenetic modifications, such as changes in global and locus-specific DNA methylation, and histone modifications are suspected to play an important role in cancer development and aging. In the present study, with the well-established horse aging model, we showed the global loss of DNA methylation in blood lymphocytes during juvenile-to-aged period....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Nuclear
Share to DNA (Cytosine-5-)-Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methyltransferase 3A

Share to DNA Methyltransferase 3B

Share to DNA Modification Methylases

Share to Insulin-Like Growth Factor II

Share to Mitotic Index

Share to Telomere Shortening

Source

Open in PubMed Open full text

Identifiers

PMID: 23700175
DOI: 10.1007/s11357-013-9541-z
PMCID: PMC3889908

Genes

DNMT1
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Changes in DNA methylation patterns and repetitive sequences in blood lymphocytes of aged horses.PMID 23700175Read ↗

DNA methylation aging and transcriptomic studies in horsesSemantic proximity Read ↗

Revisiting the genomic hypomethylation hypothesis of agingSemantic proximity Read ↗

Genome-wide epigenetic modifications in sports horses during training as an adaptation phenomenonSemantic proximity Read ↗

Copy Number of Human Ribosomal Genes With Aging: Unchanged Mean, but Narrowed Range and Decreased Variance in Elderly GroupSemantic proximity Read ↗

Imprinted Genes and Satellite Loci Are Differentially Methylated in Bovine Somatic Cell Nuclear Transfer ClonesSemantic proximity Read ↗

An integrated epigenetic and genetic analysis of DNA methyltransferase genes (DNMTs) in tumor resistant and susceptible chicken lines.Semantic proximity Read ↗

DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging ProjectSemantic proximity Read ↗

Chicken Hypothalamic and Ovarian DNA Methylome Alteration in Response to Forced MoltingSemantic proximity Read ↗

DNA methylation meta-analysis confirms the division of the genome into two functional groupsSemantic proximity Read ↗

Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissuesSemantic proximity Read ↗

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic statesSemantic proximity Read ↗

Analysis of age-related global DNA methylation in chicken.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.