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Article

An integrated epigenetic and genetic analysis of DNA methyltransferase genes (DNMTs) in tumor resistant and susceptible chicken lines.

PloS one - 16 Jul 2008

Yu Ying, Zhang Huanmin, Tian Fei, Zhang Wensheng, Fang Hongbin, Song Jiuzhou

Abstract excerpt

Both epigenetic alterations and genetic variations play essential roles in tumorigenesis. The epigenetic modification of DNA methylation is catalyzed and maintained by the DNA methyltransferases (DNMT3a, DNMT3b and DNMT1). DNA mutations and DNA methylation profiles of DNMTs themselves and their relationships with chicken neoplastic disease resistance and susceptibility are not yet defined. In the present study,...

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Source

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Identifiers

PMID: 18648519
DOI: 10.1371/journal.pone.0002672
PMCID: PMC2481300

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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