Article
Detected microsatellite polymorphisms in genetically altered inbred mouse strains.
Molecular genetics and genomics : MGG - 1 Aug 2013
Du Xiaoyan, Cui Jing, Wang Chao, Huo Xueyun, Lu Jing, Li Yichen, Chen Zhenwen
Abstract excerpt
Microsatellites are 50-200 repetitive DNA sequences composed of 1- to 6-base-pair-long reiterative motifs within the genome. They are vulnerable to DNA modifications, such as recombination and/or integration, and are recognized as "sentinel" DNA. Our previous report indicated that the genotypes of the microsatellite loci could change from mono- to poly-morphisms (CMP) in gene knockout (KO) mice, implying that...
Topics
- Animals
- Databases, Nucleic Acid
- Genetic Loci
- Genotype
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mice, Nude
- Mice, SCID
