Article
Detected microsatellite polymorphisms in genetically altered inbred mouse strains.
Molecular genetics and genomics : MGG - 1 Aug 2013
Du Xiaoyan, Cui Jing, Wang Chao, Huo Xueyun, Lu Jing, Li Yichen, Chen Zhenwen
Abstract excerpt
Microsatellites are 50-200 repetitive DNA sequences composed of 1- to 6-base-pair-long reiterative motifs within the genome. They are vulnerable to DNA modifications, such as recombination and/or integration, and are recognized as "sentinel" DNA. Our previous report indicated that the genotypes of the microsatellite loci could change from mono- to poly-morphisms (CMP) in gene knockout (KO) mice, implying that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
