Article
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing.
Blood - 15 Aug 2013
Morin Ryan D, Mungall Karen, Pleasance Erin, Mungall Andrew J, Goya Rodrigo, Huff Ryan D, Scott David W, Ding Jiarui, Roth Andrew, Chiu Readman, Corbett Richard D, Chan Fong Chun, Mendez-Lago Maria, Trinh Diane L, Bolger-Munro Madison, Taylor Greg, Hadj Khodabakhshi Alireza, Ben-Neriah Susana, Pon Julia, Meissner Barbara, Woolcock Bruce, Farnoud Noushin, Rogic Sanja, Lim Emilia L, Johnson Nathalie A, Shah Sohrab, Jones Steven, Steidl Christian, Holt Robert, Birol Inanc, Moore Richard, Connors Joseph M, Gascoyne Randy D, Marra Marco A
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous cancer composed of at least 2 molecular subtypes that differ in gene expression and distribution of mutations. Recently, application of genome/exome sequencing and RNA-seq to DLBCL has revealed numerous genes that are recurrent...
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