Article
SNPInterForest: a new method for detecting epistatic interactions.
BMC bioinformatics - 12 Dec 2011
Yoshida Makiko, Koike Asako
Abstract excerpt
BACKGROUND: Multiple genetic factors and their interactive effects are speculated to contribute to complex diseases. Detecting such genetic interactive effects, i.e., epistatic interactions, however, remains a significant challenge in large-scale association studies. RESULTS: We have developed a new method, named SNPInterForest, for identifying epistatic interactions by extending an ensemble learning technique...
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