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Article

Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model.

BMC cancer - 22 May 2013

Hu Tao, Zhang Chunhua, Tang Qiongling, Su Yanan, Li Bo, Chen Long, Zhang Zheng, Cai Tianchi, Zhu Yuechun

Abstract excerpt

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD), elevated in tumor cells, catalyzes the first reaction in the pentose-phosphate pathway. The regulation mechanism of G6PD and pathological change in human melanoma growth remains unknown. METHODS: HEM (human epidermal melanocyte) cells and huma...

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Source

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Identifiers

PMID: 23693134
DOI: 10.1186/1471-2407-13-251
PMCID: PMC3765728

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23693134-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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