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Article

Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility.

BMC gastroenterology - 20 May 2013

Servidoni Maria F, Sousa Marisa, Vinagre Adriana M, Cardoso Silvia R, Ribeiro Maria A, Meirelles Luciana R, de Carvalho Rita B, Kunzelmann Karl, Ribeiro Antônio F, Ribeiro José D, Amaral Margarida D

Abstract excerpt

BACKGROUND: Measurements of CFTR function in rectal biopsies ex vivo have been used for diagnosis and prognosis of Cystic Fibrosis (CF) disease. Here, we aimed to evaluate this procedure regarding: i) viability of the rectal specimens obtained by biopsy forceps for ex vivo bioelectrical and biochemical laboratory analyses; and ii) overall assessment (comfort, invasiveness, pain, sedation requirement, etc.) of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23688510
DOI: 10.1186/1471-230X-13-91
PMCID: PMC3679995

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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