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Article

Granulocyte colony stimulating factor alters the phenotype of neuroblastoma cells: implications for disease-free survival of high-risk patients.

Journal of pediatric surgery - 1 May 2008

Gay Andre N, Chang Shirong, Rutland Lindsey, Yu Ling, Byeseda Sarah, Naik-Mathuria Bindi, Cass Darrell L, Russell Heidi, Olutoye Oluyinka O

Abstract excerpt

INTRODUCTION: Granulocyte colony stimulating factor (GCSF) is commonly used for the treatment of chemotherapy-induced neutropenia. Despite high-dose intensive chemotherapy for advanced-stage neuroblastoma, the survival rate remains poor. Granulocyte colony stimulating factor therapy is quite common in these children; thus, we questioned its effect on neuroblastoma cells. We hypothesized that exogenous GCSF...

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Identifiers

PMID: 18485949
DOI: 10.1016/j.jpedsurg.2007.12.024
PMCID: PMC2577882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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