Article
Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment.
Parasitology - 1 Mar 2013
Standley C J, Mugisha L, Adriko M, Arinaitwe M, Rukundo J, Ajarova L, Mopya S, Betson M, Kabatereine N B, Stothard J R
Abstract excerpt
Despite treatment with praziquantel (PZQ) at 40 mg/kg in food, several chimpanzees on Ngamba Island Chimpanzee Sanctuary (NICS) continue to excrete eggs of Schistosoma mansoni. To monitor disease, 8 animals were closely examined under anaesthesia in March 2011 with portable ultrasonography and by rectal snip biopsy. Schistosome genetic diversity had been previously assayed within 4 of these chimpanzees, finding...
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