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Article

The use of cell-free fetal DNA in maternal plasma for noninvasive prenatal linkage analysis in beta globin gene cluster.

Bratislavske lekarske listy - 1 Jan 2015

Khordadpoor-Deilamani F, Akbari M T

Abstract excerpt

OBJECTIVES: To use the PCR-RFLP-based linkage analysis for non-invasive prenatal diagnosis of β-thalassemia. BACKGROUNDS: Thalassemia is a prevalent genetic disorder occurring throughout the world. Cell-free fetal DNA (cffDNA) in the maternal plasma during pregnancy has been used to develop non-invasive prenatal screening and diagnostic tests. METHODS: PCR-RFLP for six SNPs in the β-globin gene was executed on...

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PMID: 26621163
DOI: 10.4149/bll_2015_130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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