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[Diagnosis of several common alpha-thalassemia genotypes by multiplex fluorescence polymerase chain reaction].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University - 1 Apr 2003

Wen Shu, Wu Ling-qian, Li Qi

Abstract excerpt

OBJECTIVE: To develop an approach to a quick and accurate genetic diagnosis. METHODS: Byusing fluorescence primer, the fragments of alpha 1 and alpha 2-globin gene and internal control: beta-actin were amplified and then the PCR products were analyzed with Perkin Elmer ABI PRISMTM 377DNA Sequencer. Linkage analysis was also performed with (CA)n at the upstream of alpha 2-globin gene. The two methods were...

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PMID: 12934354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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