Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[α-Enolase (ENO1) inhibits epithelial-mesenchymal transition in the A549 cell line by suppressing ERK1/2 phosphorylation].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 May 2013

Zhou Xin, Zhang Ying, Han Naijun, Guo Suping, Xiao Ting, Cheng Shujun, Gao Yanning, Zhang Kaitai

Abstract excerpt

BACKGROUND AND OBJECTIVE: It has been proven that epithelial-mesenchymal transition (EMT) is a critical process which is precisely regulated by multiple signaling pathways during the progression and metastasis of non-small cell lung cancer (NSCLC). Canonical MAPK signaling is essential to transforming growth factor β (TGFβ)-induced EMT. Using the NSCLC cell line A549 as a model, the aim of this study is to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Cell Movement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Lung Neoplasms

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to Phosphopyruvate Hydratase

Share to Phosphorylation

Source

Open in PubMed Open full text

Identifiers

PMID: 23676977
DOI: 10.3779/j.issn.1009-3419.2013.05.01
PMCID: PMC6000606

Genes

ENO1
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

[α-Enolase (ENO1) inhibits epithelial-mesenchymal transition in the A549 cell line by suppressing ERK1/2 phosphorylation].PMID 23676977Read ↗

Neuron Specific Enolase Promotes Metastasis by Activating the Wnt/β-catenin Pathway in Small Cell Lung CancerSemantic proximity Read ↗

Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in gliomaSemantic proximity Read ↗

Aldolase A promotes epithelial‐mesenchymal transition to increase malignant potentials of cervical adenocarcinomaSemantic proximity Read ↗

Nell-1-ΔE, a novel transcript of Nell-1, inhibits cell migration by interacting with enolase-1.Semantic proximity Read ↗

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways.Semantic proximity Read ↗

EGF Induces Migration Independent of EMT or Invasion in A549 Lung Adenocarcinoma CellsSemantic proximity Read ↗

Treatment with insulin-like growth factor 1 receptor inhibitor reverses hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer.Semantic proximity Read ↗

Inhibition of MTA1 by ERα contributes to protection hepatocellular carcinoma from tumor proliferation and metastasisSemantic proximity Read ↗

E1a induces the expression of epithelial characteristics.Semantic proximity Read ↗

Melatonin Inhibits the Migration of Human Lung Adenocarcinoma A549 Cell Lines Involving JNK/MAPK PathwaySemantic proximity Read ↗

Reelin Is Involved in Transforming Growth Factor-β1-Induced Cell Migration in Esophageal Carcinoma CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.