Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma

21 Mar 2014

Abstract excerpt

BACKGROUND: The success of using glycolytic inhibitors for cancer treatment relies on better understanding the roles of each frequently deregulated glycolytic genes in cancer. This report analyzed the involvement of a key glycolytic enzyme, alpha-enolase (ENO1), in tumor progression and prognosis of human glioma. METHODS: ENO1 expression levels were examined in glioma tissues and normal brain (NB) tissues. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Research and Treatments
Share to Peptidase Inhibition and Analysis
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24650096
DOI: 10.1186/1476-4598-13-65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in gliomaPMID 24650096Read ↗

Beyond ENO1, emerging roles and targeting strategies of other enolases in cancersSemantic proximity Read ↗

Comprehensive Analysis of Glycolytic Enzymes as Therapeutic Targets in the Treatment of GlioblastomaSemantic proximity Read ↗

Aldolase A as a prognostic factor and mediator of progression via inducing epithelial–mesenchymal transition in gastric cancerSemantic proximity Read ↗

ENO3 promotes colorectal cancer progression by enhancing cell glycolysisSemantic proximity Read ↗

Enolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patientsSemantic proximity Read ↗

Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysisSemantic proximity Read ↗

Aldolase A promotes epithelial‐mesenchymal transition to increase malignant potentials of cervical adenocarcinomaSemantic proximity Read ↗

ALDOC and PGK1 coordinately induce glucose metabolism reprogramming and promote development of colorectal cancerSemantic proximity Read ↗

A glycolysis-based ten-gene signature correlates with the clinical outcome, molecular subtype and IDH1 mutation in glioblastoma.Semantic proximity Read ↗

COL4A1 as a novel oncogene associated with the clinical characteristics of malignancy predicts poor prognosis in gliomaSemantic proximity Read ↗

High Expression of Glycolytic Genes in Clinical Glioblastoma Patients Correlates with Lower SurvivalSemantic proximity Read ↗

Oncogenic roles of astrocyte elevated gene-1 (AEG-1) in osteosarcoma progression and prognosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.