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Genomic and expression analysis of the vanG-like gene cluster of Clostridium difficile

16 May 2013

Abstract excerpt

Primary antibiotic treatment of Clostridium difficile intestinal diseases requires metronidazole or vancomycin therapy. A cluster of genes homologous to enterococcal glycopeptides resistance vanG genes was found in the genome of C. difficile 630, although this strain remains sensitive to vancomycin. This vanG-like gene cluster was found to consist of five ORFs: the regulatory region consisting of vanR and vanS...

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Share to Antimicrobial Resistance in Staphylococcus
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PMID: 23676437
DOI: 10.1099/mic.0.065060-0

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