Article
Congenic strains of the filamentous form of Cryptococcus neoformans for studies of fungal morphogenesis and virulence.
Infection and immunity - 1 Jul 2013
Zhai Bing, Zhu Pinkuan, Foyle Dylan, Upadhyay Srijana, Idnurm Alexander, Lin Xiaorong
Abstract excerpt
Cryptococcus neoformans is an unconventional dimorphic fungus that can grow either as a yeast or in a filamentous form. To facilitate investigation of genetic factors important for its morphogenesis and pathogenicity, congenic a and α strains for a filamentous form were constructed. XL280 (α) was selected as the background strain because of its robust ability to undergo the morphological transition from yeast to...
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