Interaction Between Genetic Background and the Mating-Type Locus in <i>Cryptococcus neoformans</i> Virulence Potential

Abstract excerpt

The study of quantitative traits provides a window on the interactions between multiple unlinked genetic loci. The interaction between hosts and pathogenic microbes, such as fungi, involves aspects of quantitative genetics for both partners in this dynamic equilibrium. One important pathogenic fungus is Cryptococcus neoformans, a basidiomycete yeast that can infect the human brain and whose mating system has two...

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