Article
The rate and effects of spontaneous mutation on fitness traits in the social amoeba, Dictyostelium discoideum.
G3 (Bethesda, Md.) - 8 Jul 2013
Hall David W, Fox Sara, Kuzdzal-Fick Jennie J, Strassmann Joan E, Queller David C
Abstract excerpt
We performed a mutation accumulation (MA) experiment in the social amoeba Dictyostelium discoideum to estimate the rate and distribution of effects of spontaneous mutations affecting eight putative fitness traits. We found that the per-generation mutation rate for most fitness components is 0.0019 mutations per haploid genome per generation or larger. This rate is an order of magnitude higher than estimates for...
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