Article
Induction of a syngeneic graft-versus-leukemia effect following bone marrow transplantation for chronic myeloid leukemia.
Leukemia - 1 Apr 1990
Mackinnon S, Hows J M, Goldman J M
Abstract excerpt
Although clinical data support the concept of a graft-versus-leukemia (GVL) effect following allogeneic bone marrow transplantation (BMT), there are few data to support a similar GVL activity following syngeneic BMT in man. To identify cells with a potential antileukemic activity post-BMT, we mon...
Topics
- Adult
- Antigens, Neoplasm
- Antigens, Surface
- Bone Marrow Transplantation
- Colony-Forming Units Assay
- Graft vs Host Reaction
- Granulocytes
- Humans
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukocytes, Mononuclear
- Macrophages
- Male
- Phenotype
- Transplantation, Isogeneic