Article
Molecular characterization of the dimer formation of Fcα/μ receptor (CD351).
Molecular immunology - 1 Nov 2013
Takagaki Kana, Satoh Kazuki, Honda Shin-ichiro, Shibuya Akira
Abstract excerpt
Fcα/μR (CD351) is an Fc receptor for both IgA and IgM and forms an atypical dimer that is resistant to reduction by 2-mercaptoethanol or boiling. We previously demonstrated that the cytoplasmic portion of Fcα/μR is required for dimer formation and for its efficient cell-surface expression. However, the biochemical nature of these phenomena has not been determined. By using a BW5147 mouse cell line expressing...
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