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A rare case with typical acute promyelocytic leukemia morphology associated with isolated isochromosome 17q withoutRARα rearrangement

1 Jan 2013

Abstract excerpt

Isolated isochromosome 17q has rarely been reported in hematologic tumor patients. A 37-year-old man was admitted with fever and weakness. Blood routine test showed anemia and thrombocytopenia. The morphology and immunology of bone marrow cells conform to classic acute promyelocytic leukemia (APL). But the karyotype showed isolated isochromosome 17q without t(15;17) (q22;q12). Rverse transcriptase polymerase...

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PMID: 23664605
DOI: 10.1016/j.hemonc.2013.02.004

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