Article
Signal transducer and activator of transcription 4 gene polymorphisms associated with rheumatoid arthritis in Northwestern Chinese Han population.
Life sciences - 1 Aug 2011
Liang Ya-Ling, Wu Hua, Li Pei-Qiang, Xie Xiao-Dong, Shen Xi, Yang Xiao-Qing, Cheng Xuan, Liang Li
Abstract excerpt
AIMS: Signal transducer and activator of transcription 4 (STAT4) gene encode a transcriptional factor that transmits signals induced by several key cytokines which play important roles in the development of autoimmune diseases. Recently, several single nucleotide polymorphisms (SNPs) in STAT4 gene have been reported to be significantly associated with Rheumatoid arthritis (RA) in different ethnic populations. We...
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