Article
The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes.
Annals of hematology - 1 Oct 2013
Fu Bin, Ok Chi Young, Goswami Maitrayee, Xei Wei, Jaso Jesse M, Muzzafar Tariq, Bueso-Ramos Carlos, Verstovsek Srdan, Garcia-Manero Guillermo, Medeiros L Jeffrey, Wang Sa A
Abstract excerpt
The presence of moderate to severe bone marrow (BM) fibrosis has been shown to be an adverse feature in patients with primary myelodysplastic syndromes (MDS). However, the clinical importance of BM fibrosis is not clear in therapy-related MDS. We retrieved all therapy-related MDS (t-MDS) cases (n = 266) diagnosed at our hospital over a 10-year period (2003-2012). Reticulin and trichrome stains were performed in...
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