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Article

Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies.

Haematologica - 1 Jun 2016

Zahr Abdallah Abou, Salama Mohamed E, Carreau Nicole, Tremblay Douglas, Verstovsek Srdan, Mesa Ruben, Hoffman Ronald, Mascarenhas John

Abstract excerpt

Bone marrow fibrosis is a central pathological feature and World Health Organization major diagnostic criterion of myelofibrosis. Although bone marrow fibrosis is seen in a variety of malignant and non-malignant disease states, the deposition of reticulin and collagen fibrosis in the bone marrow of patients with myelofibrosis is believed to be mediated by the myelofibrosis hematopoietic stem/progenitor cell,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27252511
DOI: 10.3324/haematol.2015.141283
PMCID: PMC5013940

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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