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SF3B1 Mutation but Not Ring Sideroblasts Identifies a Specific Group of Myelodysplastic Syndrome-Refractory Cytopenia With Multilineage Dysplasia.

Clinical lymphoma, myeloma & leukemia - 1 May 2020

Xiong Bei, Xue Mei, Yu Yalan, Wu Sanyun, Zuo Xuelan

Abstract excerpt

BACKGROUND: Integrating the proportion of ring sideroblasts and SF3B1 mutation status is required for diagnosis of sideroblastic subgroups in myelodysplastic syndrome (MDS) as proposed by the World Health Organization 2016 classification. However, the clinical implications of SF3B1 mutation and ring sideroblasts in MDS-refractory cytopenia with multilineage dysplasia (MDS-RCMD) remain unclear. PATIENTS AND...

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PMID: 32037286
DOI: 10.1016/j.clml.2020.01.005

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