Article
Association between IL1B (+3954) polymorphisms and IL-1β levels in blood and saliva, together with acute graft-versus-host disease.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jul 2013
Resende Renata Gonçalves, Abreu Mauro Henrique Nogueira Guimarães, de Souza Leandro Napier, Silva Maria Elisa Souza, Gomez Ricardo Santiago, Correia-Silva Jeane de Fátima
Abstract excerpt
Graft-versus-host disease (GVHD) is associated with morbidity and mortality in the recipients of allogeneic hematopoietic stem cell transplants (allo-HSCTs). Interleukin-1β (IL-1β) is a potent inflammatory mediator involved in different inflammatory conditions. Therefore, we aimed to investigate the association of IL1B gene polymorphism in recipients and donors in cases in which acute GVHD (aGVHD) has been...
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