Article
Novel hereditary forms of pheochromocytomas and paragangliomas.
Frontiers of hormone research - 1 Jan 2013
Dahia Patricia L M
Abstract excerpt
Pheochromocytomas and paragangliomas are catecholamine-secreting tumors of neural crest origin that arise from the adrenal medulla or extra-adrenal sympathetic paraganglia, respectively. Over the last decade, the extensive genetic heterogeneity of these tumors came to light with the identification of multiple susceptibility genes. These mutations account for at least one-third of pheochromocytomas and...
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