Article
Molecular markers of paragangliomas/pheochromocytomas.
Oncotarget - 11 Apr 2017
Zhikrivetskaya Svetlana O, Snezhkina Anastasiya V, Zaretsky Andrew R, Alekseev Boris Y, Pokrovsky Anatoly V, Golovyuk Alexander L, Melnikova Nataliya V, Stepanov Oleg A, Kalinin Dmitry V, Moskalev Alexey A, Krasnov George S, Dmitriev Alexey A, Kudryavtseva Anna V
Abstract excerpt
Paragangliomas/pheochromocytomas comprise rare tumors that arise from the extra-adrenal paraganglia, with an incidence of about 2 to 8 per million people each year. Approximately 40% of cases are due to genetic mutations in at least one out of more than 30 causative genes. About 25-30% of pheochromocytomas/paragangliomas develop under the conditions of a hereditary tumor syndrome a third of which are caused by...
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