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Pheochromocytoma and paraganglioma syndromes: genetics and management update

7 Nov 2013

Abstract excerpt

Pheochromocytomas (pheos) and paragangliomas (pgls) are rare tumours of the autonomic nervous system, originating from paraganglia, which are dispersed neuroendocrine organs characterized by catecholamine and peptide-producing cells derived from the neural crest. Medical textbooks have traditionally suggested that 10% of pheos are heritable. However, the frequency of heritable pheo has been underestimated. Three...

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PMID: 24523625
DOI: 10.3747/co.21.1579

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